Board Thread:Card Unit Builds/@comment-25228151-20140804062429/@comment-25067771-20140804064054

Empusa's 50% defense debuff will not allow for double damage. If you deal 50,000 damage to a 10,000 defense target, then with the Empusa debuff you will not do 100,000; you will do roughly 55,000.

That said, even though you lose the sadistic buff, you should probably put a different card in. The rest is okay ish. Eventually you'll want to swap out High Vampire because 25% increase damage is outclassed by damage cards.